Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861699 | 1.00 | LMNA (0.59) | LMNAMEN1KMT2ANOTUMTSHR | |
| SCHEMBL1867501 | 1.00 | LMNA (0.59) | LMNAMEN1KMT2ANOTUMTSHR | |
| SCHEMBL1865415 | 1.00 | LMNA (0.59) | LMNAMEN1KMT2ANOTUMTSHR | |
| SCHEMBL1865452 | 1.00 | LMNA (0.59) | LMNAMEN1KMT2ANOTUMTSHR | |
| SCHEMBL13276088 | 1.00 | LMNA (0.59) | LMNAMEN1KMT2ANOTUMTSHR | |
| SCHEMBL10362088 | 0.82 | NOTUM (0.53) | LMNANOTUMTSHRRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7438226 | 0.81 | NOTUM (0.52) | LMNANOTUMTSHRPKMALDH1A1 | |
| SCHEMBL1867247 | 0.81 | PKM (0.62) | LMNAMEN1KMT2ANOTUMTSHR | |
| SCHEMBL10859231 | 0.80 | NOTUM (0.69) | LMNAMEN1KMT2ANOTUMTSHR | |
| SCHEMBL20462830 | 0.75 | NOTUM (0.75) | LMNAMEN1KMT2ANOTUMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | claimed |
| EP-2493853-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2012-09-05 | — | — | EP | claimed |
| WO-2011051394-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-05-05 | — | — | WO | claimed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| EP-2493853-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051394-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | OR10J3, CBR3, C9 | LMNA 3667/4885MEN1 2467/4885KMT2A 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.