Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861699 | 0.81 | LMNA (0.59) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1865415 | 0.81 | LMNA (0.59) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1865417 | 0.81 | LMNA (0.59) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1867501 | 0.81 | LMNA (0.59) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13276088 | 0.81 | LMNA (0.59) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1865452 | 0.81 | LMNA (0.59) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10859231 | 0.77 | NOTUM (0.69) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1866260 | 0.76 | PKM (0.71) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10854008 | 0.75 | PKM (0.90) | PKMNOTUMALDH1A1MAPTLMNA | |
| SCHEMBL1861546 | 0.74 | MAPT (0.83) | PKMNOTUMALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | claimed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| EP-2493853-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051394-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011051394-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | OR10J3, CBR3, C9 | PKM 1697/4885CACNA1H 4134/4885NOTUM 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.