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Sugi Predict / Compounds / SCHEMBL18654362

SCHEMBL18654362

SCHEMBL18654362

O=C(OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC[C@H]3O[C@@H](OC[C@H]4O[C@@H](OCCCCCO)[C@H](OC(=O)c5ccccc5)[C@@H](OC(=O)c5ccccc5)[C@@H]4OC(=O)c4ccccc4)[C@H](OC(=O)c4ccccc4)[C@@H](O)[C@@H]3OC(=O)c3ccccc3)[C@H](OC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@@H]2OC(=O)c2ccccc2)[C@H](OC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 10/20 0.44
▸ USP2 O75604 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ F11 P03951 2/20 0.41
▸ TMPRSS2 O15393 1/20 0.41
▸ PDE5A O76074 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ HMGCR P04035 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ LCK P06239 1/20 0.41
▸ FYN P06241 1/20 0.41
▸ HSPD1 P10809 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CA6 P23280 1/20 0.41
▸ TBXAS1 P24557 1/20 0.41
▸ MAPK3 P27361 1/20 0.41
▸ MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18654363 0.95 PTPN1 (0.48) PTPN1USP2MEN1POLBKMT2A
SCHEMBL19461180 0.93 PTPN1 (0.50) PTPN1USP2MEN1POLBKMT2A
SCHEMBL13250757 0.93 PTPN1 (0.50) PTPN1USP2MEN1POLBKMT2A
SCHEMBL17850303 0.93 PTPN1 (0.50) PTPN1USP2MEN1POLBKMT2A
SCHEMBL8348286 0.90 PTPN1 (0.51) PTPN1USP2MEN1POLBKMT2A
SCHEMBL8348283 0.90 PTPN1 (0.51) PTPN1USP2MEN1POLBKMT2A
SCHEMBL18654230 0.90 PTPN1 (0.42) PTPN1USP2MEN1POLBKMT2A
SCHEMBL1238439 0.89 PTPN1 (0.56) PTPN1USP2MEN1POLBKMT2A
SCHEMBL18650659 0.87 PTPN1 (0.41) PTPN1USP2MEN1POLBKMT2A
SCHEMBL26510429 0.86 PTPN1 (0.47) PTPN1USP2MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10266609-B2 Immunomodulating beta-1,6-D-glucans INNATE BIOTHERAPEUTICS, LLC (US) 2019-04-23 — — US disclosed
US-20170081428-A1 IMMUNOMODULATING BETA-1,6-D-GLUCANS INNATE BIOTHERAPEUTICS, LLC 2017-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10266609-B2 Immunomodulating beta-1,6-D-glucans IFNG, FUT6, LGALS1 PTPN1 797/4885USP2 4100/4885MEN1 1126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.