Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028371 | 0.82 | APP (0.53) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL18195254 | 0.81 | POLB (0.51) | ALDH1A1CNR2HSD17B10MEN1MAPT | |
| SCHEMBL20814168 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL10299737 | 0.74 | NR1H3 (0.47) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL21729751 | 0.73 | CNR2 (0.43) | ALDH1A1CNR2MEN1MAPTKMT2A | |
| SCHEMBL18906447 | 0.72 | CNR2 (0.50) | ALDH1A1CNR2MEN1KMT2AALOX15 | |
| SCHEMBL15120734 | 0.72 | CNR2 (0.50) | ALDH1A1CNR2MEN1KMT2AALOX15 | |
| SCHEMBL10053401 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL26669939 | 0.70 | MEN1 (0.48) | CNR2MEN1KMT2A | |
| SCHEMBL2616778 | 0.70 | APP (0.67) | ALDH1A1HSD17B10MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | PPOX, OSTC, OCIAD1 | ALDH1A1 2904/4885CNR2 4148/4885HSD17B10 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.