Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23762934 | 0.85 | ALOX15 (0.43) | ATMALDH1A1KDM4EALOX15CA1 | |
| SCHEMBL18497935 | 0.84 | KDM4E (0.31) | ALDH1A1KDM4EUSP2 | |
| SCHEMBL23992155 | 0.79 | ATM (0.34) | ATMALDH1A1KDM4EALOX15CA1 | |
| SCHEMBL18655405 | 0.75 | CTSK (0.44) | CA1CA2 | |
| SCHEMBL31493487 | 0.75 | ATM (0.39) | ATMALDH1A1KDM4EALOX15CA1 | |
| SCHEMBL31493463 | 0.75 | ALDH1A1 (0.41) | ATMALDH1A1KDM4EALOX15CA1 | |
| SCHEMBL31493445 | 0.75 | ALDH1A1 (0.41) | ATMALDH1A1KDM4EALOX15CA1 | |
| SCHEMBL16790598 | 0.73 | ATM (0.38) | ATMALDH1A1KDM4EALOX15CA1 | |
| SCHEMBL21434164 | 0.73 | ATM (0.42) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL8613134 | 0.73 | HDAC4 (0.39) | ATMALDH1A1KDM4EALOX15CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193516-A2 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-10 | — | — | WO | disclosed |
| WO-2017045510-A1 | Β-LACTAMASE INHIBITOR AND APPLICATION THEREOF | 山东轩竹医药科技有限公司 | 2017-03-23 | — | — | WO | disclosed |