SCHEMBL1865622

SCHEMBL1865622

C=C(CCCCCCCCCCC(=C)C(N)=O)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
PMP22 Q01453 1/20 0.38
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PLG P00747 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
SLC6A2 P23975 1/20 0.36
RECQL P46063 1/20 0.36
SLC6A3 Q01959 1/20 0.36
OR51E2 Q9H255 1/20 0.35
PAOX Q6QHF9 1/20 0.35
FAAH O00519 3/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1858134 1.00 LMNA (0.38) LMNATDP1TSHRNFKB1PMP22
SCHEMBL435733 1.00 LMNA (0.38) LMNATDP1TSHRNFKB1PMP22
SCHEMBL730324 1.00 LMNA (0.38) LMNATDP1TSHRNFKB1PMP22
SCHEMBL732893 1.00 LMNA (0.38) LMNATDP1TSHRNFKB1PMP22
SCHEMBL17672227 1.00 LMNA (0.38) LMNATDP1TSHRNFKB1PMP22
SCHEMBL731200 1.00 LMNA (0.38) LMNATDP1TSHRNFKB1PMP22
SCHEMBL1862317 1.00 LMNA (0.38) LMNATDP1TSHRNFKB1PMP22
SCHEMBL10901940 0.97 TDP1 (0.40) LMNATDP1TSHRNFKB1PMP22
SCHEMBL10593694 0.95 KMT2A (0.40) LMNATDP1TSHRNFKB1PMP22
SCHEMBL9065831 0.95 KMT2A (0.40) LMNATDP1TSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2363151-B1 POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME SUNGKYUNKWAN UNIV FOUNDATION FOR CORPORATE COLLABORATION (KR) 2018-10-17 EP claimed
US-8383153-B2 Poly(amidoamine) oligomer hydrogel for drug delivery and drug carrier using the same SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2013-02-26 US claimed
US-20110217376-A1 POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2011-09-08 US claimed
EP-2363151-A1 Poly(amidoamine) oligomer hydrogel for drug delivery and drug carrier using the same Sungkyunkwan University Foundation For Corporate Collaboration (KR) 2011-09-07 EP claimed
US-7935742-B2 Ink composition, inkjet recording method, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2011-05-03 US claimed
US-20070206053-A1 Ink composition, inkjet recording method, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-06 US claimed
EP-2363151-B1 POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME SUNGKYUNKWAN UNIV FOUNDATION FOR CORPORATE COLLABORATION (KR) 2018-10-17 EP disclosed
US-8383153-B2 Poly(amidoamine) oligomer hydrogel for drug delivery and drug carrier using the same SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2013-02-26 US disclosed
US-20110217376-A1 POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2011-09-08 US disclosed
EP-2363151-A1 Poly(amidoamine) oligomer hydrogel for drug delivery and drug carrier using the same Sungkyunkwan University Foundation For Corporate Collaboration (KR) 2011-09-07 EP disclosed
US-7935742-B2 Ink composition, inkjet recording method, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2011-05-03 US disclosed
US-20070206053-A1 Ink composition, inkjet recording method, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
EP-1829941-A1 Ink composition, inkjet recording method, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM Corporation (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110217376-A1 POLY(AMIDOAMINE) OLIGOMER HYDROGEL FOR DRUG DELIVERY AND DRUG CARRIER USING THE SAME PAM, ACMSD, APEH LMNA 2990/4885TDP1 770/4885TSHR 2374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.