Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FABP7 | O15540 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214483 | 0.84 | ALDH1A1 (0.49) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL6876401 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL6758987 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL1907855 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL24410821 | 0.81 | TSHR (0.49) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL3160414 | 0.81 | TSHR (0.46) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL6758990 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL17270483 | 0.80 | FABP7 (0.48) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL965392 | 0.80 | FABP7 (0.48) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 | |
| SCHEMBL12914975 | 0.80 | TSHR (0.48) | ALDH1A1TSHRCYP3A4CASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808531-B2 | Compounds and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | Graybug Vision, Inc. (US) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170080092-A1 | Compounds And Compositions for the Treatment of Ocular Disorders | PTGIR, PTGIS, CA2 | ALDH1A1 1010/4885TSHR 897/4885CYP3A4 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.