Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18341978 | 0.87 | MEN1 (0.35) | MEN1NR2F2KMT2ADYRK1AADK | |
| SCHEMBL18656782 | 0.83 | MEN1 (0.33) | MEN1NR2F2KMT2ADYRK1AADK | |
| SCHEMBL18656761 | 0.78 | MEN1 (0.41) | MEN1NR2F2KMT2ADYRK1AADK | |
| SCHEMBL18341927 | 0.71 | RET (0.37) | MEN1NR2F2KMT2AADKADORA2A | |
| SCHEMBL1923920 | 0.70 | PDE2A (0.37) | MEN1NR2F2KMT2AADKSRC | |
| SCHEMBL12590024 | 0.69 | MEN1 (0.36) | MEN1NR2F2KMT2AADKSRC | |
| SCHEMBL18342002 | 0.69 | LMNA (0.42) | SRCADORA2AADORA1 | |
| SCHEMBL20492598 | 0.68 | ADORA2A (0.40) | MEN1NR2F2KMT2AADKADORA2A | |
| SCHEMBL20493241 | 0.67 | MEN1 (0.50) | MEN1NR2F2KMT2AADORA2AADORA2B | |
| SCHEMBL18342055 | 0.67 | MEN1 (0.60) | MEN1NR2F2KMT2ASRCADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046738-A1 | TRIAZOLONE COMPOUNDS AS PERK INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-03-23 | — | — | WO | disclosed |