Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10159235 | 0.89 | MEN1 (0.36) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL10159295 | 0.89 | MEN1 (0.36) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL10159277 | 0.89 | MEN1 (0.36) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL18133155 | 0.82 | IDH1 (0.35) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL10159032 | 0.75 | KMT2A (0.60) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL18656937 | 0.68 | KMT2A (0.70) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL18656955 | 0.67 | MAPT (0.50) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL10159242 | 0.66 | PIM1 (0.37) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL10159225 | 0.65 | OPRM1 (0.40) | MEN1USP2MAPTKMT2AGAA | |
| SCHEMBL10159299 | 0.65 | OPRM1 (0.40) | MEN1USP2MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144299-A1 | PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Cambria Pharmaceuticals, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |