Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18656977 | 0.97 | ALDH1A1 (0.46) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL18657003 | 0.90 | GAA (0.44) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL20179255 | 0.87 | LMNA (0.49) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL18659079 | 0.86 | GAA (0.41) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL21741384 | 0.84 | GAA (0.42) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL18628006 | 0.82 | GAA (0.48) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL21583680 | 0.82 | HPGD (0.55) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL18628005 | 0.82 | GAA (0.48) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL20386965 | 0.82 | GAA (0.48) | LMNAALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL298766 | 0.81 | LMNA (0.64) | LMNAALDH1A1L3MBTL1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017045932-A1 | ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |