Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TLR4 | O00206 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30618855 | 1.00 | LMNA (0.64) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL297297 | 0.86 | ALDH1A1 (0.48) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL31530440 | 0.86 | LMNA (0.48) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL11299077 | 0.86 | LMNA (0.48) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL5943455 | 0.84 | LMNA (0.67) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL12516805 | 0.84 | ALDH1A1 (0.69) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL467502 | 0.84 | LMNA (0.52) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL6033685 | 0.84 | HTT (0.63) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL6033676 | 0.84 | LMNA (0.63) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL9879632 | 0.83 | LMNA (0.60) | LMNAGAAKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 795 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| US-20230004023-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC. (CH) | 2023-01-05 | — | — | US | claimed |
| WO-2022263994-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2022-12-22 | — | — | WO | claimed |
| CN-110194829-A | The preparation method of high refractive index PU modified polyorganosiloxane | 广东工业大学 | 2019-09-03 | — | — | CN | claimed |
| EP-2880069-B1 | POLYUREA ELASTOMER HAVING INCREASED CHEMICAL RESISTANCE | BASF SE (DE) | 2019-03-27 | — | — | EP | claimed |
| US-9260628-B2 | Polyurea elastomers having increased chemicals resistance | BASF SE (DE) | 2016-02-16 | — | — | US | claimed |
| EP-2970559-A1 | ACTIVE POLYMER POLYOLS AND A PROCESS FOR THEIR PRODUCTION | Covestro LLC (US) | 2016-01-20 | — | — | EP | claimed |
| US-20130261207-A1 | PROCESS FOR PRODUCTION OF POLYMER POLYOLS | BAYER MATERIALSCIENCE LLC (US) | 2013-10-03 | — | — | US | claimed |
| US-8470927-B2 | Stable, low viscosity, easy handling; raw material for high speed, large volume polyurethane foam production; continuous, simultaneous alkoxylation and polymerization of starter compound having active hydrogen atoms and unsaturated monomers; double metal cyanide catalyst and free radical initiator | BAYER MATERIALSCIENCE LLC (US) | 2013-06-25 | — | — | US | claimed |
| CN-1660919-B | Process for production of polymer polyols | BAYER MATERIALSCIENCE LLC | 2012-11-14 | — | — | CN | claimed |
| US-20050192369-A1 | Process for production of polymer polyols | COVESTRO LLC | 2005-09-01 | — | — | US | claimed |
| EP-1568727-A1 | Process for production of polymer polyols | Bayer MaterialScience LLC (US) | 2005-08-31 | — | — | EP | claimed |
| CN-1660919-A | Process for production of polymer polyols | BAYER MATERIALSCIENCE LLC (US) | 2005-08-31 | — | — | CN | claimed |
| US-6426120-B1 | CONTACTING WITH ACRYLATED POLYSILOXANE; PROTECTIVE COATING | MORGAN ADHESIVES COMPANY | 2002-07-30 | — | — | US | claimed |
| EP-0370547-B1 | Graft stabilising and prestabilising copolymers, their preparation, process to obtain polymer-polyol dispersions and process to obtain polyurethane foams | NEW CARBOCHIM SA (BE) | 1994-03-16 | — | — | EP | claimed |
| US-5081180-A | Graft copolymers as polyether stabilizers | THE DOW CHEMICAL COMPANY | 1992-01-14 | — | — | US | claimed |
| EP-0370547-A1 | Graft stabilising and prestabilising copolymers, their preparation, process to obtain polymer-polyol dispersions and process to obtain polyurethane foams | NEW CARBOCHIM S.A. (BE) | 1990-05-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | LMNA 531/4885GAA 4558/4885KMT2A 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.