Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663404 | 0.81 | MAPT (0.46) | L3MBTL1MAPTSMN1; SMN2HSP90AA1HSP90AB1 | |
| SCHEMBL11816684 | 0.71 | ACMSD (0.51) | PTGS2SLC6A3L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL11856263 | 0.70 | ACMSD (0.50) | PTGS2SLC6A3L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL11673820 | 0.70 | ACMSD (0.50) | PTGS2SLC6A3L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL11856256 | 0.70 | ACMSD (0.50) | PTGS2SLC6A3L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL19690413 | 0.70 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4EPDK2 | |
| SCHEMBL18663367 | 0.69 | FGFR1 (0.39) | L3MBTL1MAPTSMN1; SMN2HSP90AA1HSP90AB1 | |
| SCHEMBL18663286 | 0.69 | CXCR5 (0.33) | SLC6A3MAPTSMN1; SMN2ACMSD | |
| SCHEMBL26352572 | 0.67 | ACMSD (0.50) | SLC6A3L3MBTL1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19690698 | 0.66 | GAA (0.38) | SLC6A3SMN1; SMN2HSP90AA1HSP90AB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-03-30 | — | — | US | claimed |
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | TEC, DGAT2, MOGAT2 | PTGS2 483/4885SLC6A3 3440/4885L3MBTL1 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.