Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 12/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663321 | 0.81 | ELANE (0.38) | THRBTDP1PDK2APEX1 | |
| SCHEMBL19690596 | 0.80 | BID (0.41) | — | |
| SCHEMBL18663353 | 0.74 | TDP1 (0.44) | THRBTDP1PDK2APEX1 | |
| SCHEMBL18663304 | 0.73 | THRB (0.64) | THRBTDP1PDK2APEX1 | |
| SCHEMBL2709811 | 0.73 | THRB (0.55) | THRBTDP1PDK2APEX1HDAC4 | |
| SCHEMBL18663338 | 0.70 | THRB (0.40) | THRBTDP1PDK2APEX1CYP2D6 | |
| SCHEMBL19690414 | 0.69 | PDK2 (0.34) | THRBTDP1PDK2 | |
| SCHEMBL23746045 | 0.67 | CYP2D6 (0.50) | THRBTDP1PDK2APEX1CYP2D6 | |
| SCHEMBL28515223 | 0.67 | THRB (0.45) | THRBTDP1PDK2APEX1CYP2D6 | |
| Bicarbonate SCHEMBL28365018 | 0.66 | FOLH1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-03-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088642-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST CONTAINING CATALYST COMPONENT AND USE THEREOF | TEC, DGAT2, MOGAT2 | THRB 3945/4885TDP1 2480/4885PDK2 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.