Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18664015 | 1.00 | MEN1 (0.36) | MEN1ALDH1A1KMT2ASIGMAR1PHGDH | |
| SCHEMBL16022954 | 0.80 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2ASIGMAR1PHGDH | |
| SCHEMBL20063989 | 0.79 | GNAI3 (0.31) | — | |
| SCHEMBL18663993 | 0.79 | — | — | |
| SCHEMBL18664001 | 0.79 | — | — | |
| SCHEMBL13873243 | 0.77 | MEN1 (0.35) | MEN1ALDH1A1KMT2ASIGMAR1PHGDH | |
| SCHEMBL105496 | 0.74 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2ASIGMAR1PHGDH | |
| SCHEMBL28316762 | 0.72 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL20064974 | 0.70 | ADH1B (0.45) | — | |
| SCHEMBL25084170 | 0.70 | MEN1 (0.39) | MEN1ALDH1A1KMT2ASIGMAR1PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017045751-A1 | COMPOUNDS AS ASIC INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |