Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20925013 | 0.97 | CES2 (0.44) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL18885205 | 0.97 | CES2 (0.44) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL18874463 | 0.97 | CES2 (0.44) | ALDH1A1CES2CES1DNM1GPR84 | |
| Iodide SCHEMBL10431384 | 0.95 | CES2 (0.42) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL25149017 | 0.80 | — | — | |
| SCHEMBL24211068 | 0.78 | CES2 (0.41) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL22986847 | 0.78 | SPHK2 (0.43) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL15997772 | 0.78 | DNM1 (0.42) | CES2CES1AKR1B1DNM1 | |
| SCHEMBL21786999 | 0.77 | CES2 (0.36) | ALDH1A1CES2CES1AKR1B1GPR84 | |
| SCHEMBL22304537 | 0.77 | DNM1 (0.41) | ALDH1A1CES2CES1DNM1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049245-A2 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2017-03-23 | — | — | WO | disclosed |