Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673901 | 0.91 | ADORA2A (0.52) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6673671 | 0.89 | ADORA2B (0.55) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6673871 | 0.88 | ADORA2B (0.57) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6673126 | 0.87 | ADORA2A (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6679184 | 0.83 | ADORA2B (0.51) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL20782416 | 0.81 | HPRT1 (0.65) | ADORA2AADORA2BADORA1 | |
| SCHEMBL6674167 | 0.79 | ADORA2A (0.43) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6674438 | 0.78 | PIK3CG (0.62) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL6428435 | 0.76 | ADORA2B (0.52) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL1866522 | 0.74 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | claimed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | claimed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | claimed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | claimed |
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | disclosed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | disclosed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | disclosed |