Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667280 | 0.88 | RAB9A (0.43) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| SCHEMBL26759213 | 0.88 | RAB9A (0.49) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| Bromide SCHEMBL18641523 | 0.87 | RAB9A (0.42) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18641385 | 0.87 | RAB9A (0.42) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| SCHEMBL21229054 | 0.85 | LSS (0.51) | RAB9AMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL18667607 | 0.85 | RAB9A (0.40) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21229039 | 0.84 | LSS (0.50) | RAB9AMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL18641426 | 0.83 | IRAK4 (0.40) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21229111 | 0.83 | KDM4E (0.48) | RAB9AMAPTLMNASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL21229131 | 0.82 | KEAP1 (0.56) | RAB9AMAPTLMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |