Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667707 | 0.96 | RAB9A (0.39) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| SCHEMBL18666990 | 0.87 | RAB9A (0.37) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| SCHEMBL18667608 | 0.85 | RAB9A (0.44) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| SCHEMBL21229098 | 0.83 | HDAC1 (0.43) | HDAC1HDAC3HDAC6XIAPSUCNR1 | |
| SCHEMBL26759213 | 0.82 | RAB9A (0.49) | RAB9AMAPTLMNANPC1SMN1; SMN2 | |
| SCHEMBL18667570 | 0.82 | HRH3 (0.44) | — | |
| SCHEMBL18667605 | 0.82 | ATP4A (0.49) | KDM4E | |
| SCHEMBL18667549 | 0.81 | ATP4A (0.41) | — | |
| SCHEMBL18667084 | 0.81 | KMT2A (0.47) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL18667123 | 0.80 | DRD4 (0.34) | RAB9AMAPTLMNAKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |