Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114035 | 1.00 | CASP1 (0.56) | CASP1ALOX15CYP3A4SMN1; SMN2PKM | |
| SCHEMBL8143538 | 0.92 | CASP1 (0.50) | CASP1ALOX15CYP3A4SMN1; SMN2PKM | |
| SCHEMBL28250094 | 0.91 | CASP1 (0.49) | CASP1ALOX15CYP3A4SMN1; SMN2PKM | |
| SCHEMBL9542594 | 0.86 | ALDH1A1 (0.53) | CASP1CYP3A4SMN1; SMN2PKMKDM4E | |
| SCHEMBL5690353 | 0.85 | KDM4E (0.52) | CASP1CYP3A4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24871065 | 0.83 | HPGD (0.57) | SMN1; SMN2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11783181 | 0.83 | CASP1 (0.61) | CASP1CYP3A4SMN1; SMN2PKMKDM4E | |
| SCHEMBL9407588 | 0.83 | CASP1 (0.59) | CASP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL13956302 | 0.82 | ALDH1A1 (0.48) | CASP1CYP3A4SMN1; SMN2PKMKDM4E | |
| SCHEMBL9090457 | 0.82 | ALOX15 (0.57) | CASP1ALOX15SMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496682-A1 | DELIVERY PARTICLE | The Procter & Gamble Company (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011056935-A1 | DELIVERY PARTICLE | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |