Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624739 | 0.81 | APP (0.65) | KMT2AMEN1GAATDP1RAB9A | |
| SCHEMBL1861620 | 0.80 | KMT2A (0.50) | KMT2AMEN1GAAGLAKDM4E | |
| SCHEMBL22624762 | 0.80 | KMT2A (0.60) | KMT2AMEN1GAAKDM4ERAB9A | |
| SCHEMBL22624694 | 0.78 | APP (0.54) | KMT2AMEN1GAATDP1MAPT | |
| SCHEMBL22624810 | 0.77 | APP (0.63) | KMT2AMEN1GAATDP1RAB9A | |
| SCHEMBL11507416 | 0.76 | APP (0.57) | KMT2AMEN1GAARAB9AMAPT | |
| SCHEMBL22624743 | 0.75 | APP (0.61) | KMT2AMEN1GAARAB9AL3MBTL1 | |
| SCHEMBL22624754 | 0.75 | MYC (0.53) | KMT2AMEN1GAATDP1RAB9A | |
| SCHEMBL22624749 | 0.75 | APP (0.55) | KMT2AMEN1GAATDP1RAB9A | |
| SCHEMBL11509750 | 0.75 | APP (0.56) | KMT2AMEN1GAATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493857-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | Ariel-University Research and Development Company Ltd. (IL) | 2012-09-05 | — | — | EP | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | MPG, PRMT9, AADAT | KMT2A 848/4885MEN1 1862/4885GAA 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.