Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | RAD52 | P43351 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866907 | 0.80 | KMT2A (0.59) | KMT2ASMN1; SMN2MEN1MAPK1MAPT | |
| SCHEMBL1870594 | 0.72 | KMT2A (0.63) | KMT2ASMN1; SMN2MEN1MAPK1MAPT | |
| SCHEMBL1589671 | 0.71 | BACE1 (0.50) | IDO1TDO2ALDH1A1EGFRNPSR1 | |
| SCHEMBL29901077 | 0.71 | BACE1 (0.50) | IDO1TDO2ALDH1A1EGFRNPSR1 | |
| SCHEMBL27570737 | 0.71 | ALOX5 (0.53) | KMT2AMEN1IDO1TDO2ALDH1A1 | |
| SCHEMBL12019870 | 0.71 | KMT2A (0.57) | KMT2ASMN1; SMN2MEN1MAPK1MAPT | |
| SCHEMBL1863835 | 0.69 | POLB (0.57) | KMT2ASMN1; SMN2MEN1MAPK1MAPT | |
| SCHEMBL7518908 | 0.68 | ITGA4 (0.54) | ALDH1A1 | |
| SCHEMBL7518902 | 0.68 | ITGA4 (0.54) | ALDH1A1 | |
| SCHEMBL4953327 | 0.68 | BACE1 (0.50) | IDO1TDO2POLBALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493857-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | Ariel-University Research and Development Company Ltd. (IL) | 2012-09-05 | — | — | EP | claimed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | claimed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | claimed |
| EP-2493857-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | Ariel-University Research and Development Company Ltd. (IL) | 2012-09-05 | — | — | EP | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | MPG, PRMT9, AADAT | KMT2A 848/4885SMN1; SMN2 3075/4885MEN1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.