Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 4/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LIPC | P11150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18669295 | 0.90 | TAAR1 (0.44) | TAAR1CPN1CPB2 | |
| SCHEMBL16528692 | 0.90 | TAAR1 (0.44) | TAAR1CPN1CPB2 | |
| SCHEMBL2898018 | 0.86 | LIPG (0.36) | DPP7TAAR1LIPGNAMPTLIPC | |
| SCHEMBL2005065 | 0.85 | IGF2R (0.32) | TAAR1 | |
| SCHEMBL16414502 | 0.84 | LIPG (0.42) | DPP7TAAR1LIPGNAMPTLIPC | |
| SCHEMBL22835620 | 0.84 | LIPG (0.42) | DPP7TAAR1LIPGNAMPTLIPC | |
| SCHEMBL22835940 | 0.84 | LIPG (0.42) | DPP7TAAR1LIPGNAMPTLIPC | |
| SCHEMBL18426120 | 0.81 | KMT2A (0.42) | TAAR1LIPGLIPC | |
| SCHEMBL18426119 | 0.81 | KMT2A (0.42) | TAAR1LIPGLIPC | |
| SCHEMBL2146187 | 0.80 | TAAR1 (0.36) | DPP7TAAR1LIPGNAMPTLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353162-A1 | PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2018-08-01 | — | — | EP | disclosed |
| WO-2017050714-A1 | PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-03-30 | — | — | WO | disclosed |