SCHEMBL2898018

SCHEMBL2898018

O=C(O)N1CC[C@@H](OCCF)C1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 7/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ADORA2A P29274 1/20 0.32
LIPC P11150 2/20 0.32
DPP7 Q9UHL4 1/20 0.32
NAMPT P43490 1/20 0.32
LSS P48449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16414502 0.88 LIPG (0.42) LIPGTAAR1LIPCDPP7NAMPT
SCHEMBL22835940 0.88 LIPG (0.42) LIPGTAAR1LIPCDPP7NAMPT
SCHEMBL22835620 0.88 LIPG (0.42) LIPGTAAR1LIPCDPP7NAMPT
SCHEMBL18669362 0.86 DPP7 (0.37) LIPGTAAR1LIPCDPP7NAMPT
SCHEMBL18426119 0.81 KMT2A (0.42) LIPGTAAR1LIPC
SCHEMBL18426120 0.81 KMT2A (0.42) LIPGTAAR1LIPC
SCHEMBL2146187 0.80 TAAR1 (0.36) LIPGTAAR1LIPCDPP7NAMPT
SCHEMBL23364561 0.79 LIPG (0.37) LIPGTAAR1LIPC
SCHEMBL21767377 0.79 NAMPT (0.37) LIPGTAAR1LIPCDPP7NAMPT
SCHEMBL21767375 0.79 NAMPT (0.37) LIPGTAAR1LIPCDPP7NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732456-B2 Pyridone derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2010-06-08 US disclosed
US-20070208046-A1 Pyridone derivative MSD K.K. (JP) 2007-09-06 US disclosed
EP-1741703-A1 PYRIDONE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208046-A1 Pyridone derivative CHRM1, XDH, MTR LIPG 4860/4885TAAR1 92/4885ADORA2A 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.