Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810689 | 0.90 | HDAC1 (0.53) | GSK3BHDAC1HDAC3HDAC2 | |
| SCHEMBL18670958 | 0.85 | HDAC1 (0.71) | GSK3BHDAC1HDAC3HDAC2 | |
| SCHEMBL18670987 | 0.85 | HDAC1 (0.54) | GSK3BHDAC1HDAC3HDAC2 | |
| SCHEMBL3646469 | 0.84 | HDAC1 (0.60) | GSK3BHDAC1HDAC3HDAC2 | |
| SCHEMBL18653510 | 0.82 | HDAC1 (0.73) | HDAC1HDAC3HDAC2 | |
| SCHEMBL20806987 | 0.82 | LIPG (0.48) | GSK3BTRPV1HDAC1ITK | |
| SCHEMBL3777895 | 0.82 | HDAC1 (0.54) | GSK3BHDAC1HDAC3HDAC2 | |
| SCHEMBL18670955 | 0.81 | GSK3B (0.55) | GSK3BHDAC1HDAC3HDAC2ITK | |
| SCHEMBL18670976 | 0.81 | LDHA (0.56) | GSK3BHDAC1HDAC3HDAC2 | |
| SCHEMBL2227269 | 0.80 | CHEK2 (0.62) | GSK3BHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603950-B1 | Compounds of imaging agent with HDAC inhibitor for treatment of Alzheimer syndrome and method of synthesis thereof | INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2017-03-28 | — | — | US | disclosed |
| US-9603950-B1 | Compounds of imaging agent with HDAC inhibitor for treatment of Alzheimer syndrome and method of synthesis thereof | INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2017-03-28 | — | — | US | disclosed |