Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561531 | 1.00 | LMNA (0.43) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL14929037 | 1.00 | LMNA (0.43) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL19866479 | 0.87 | LGALS9 (0.49) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL14616525 | 0.86 | LGALS9 (0.40) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL14853797 | 0.86 | POLB (0.47) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL24522365 | 0.86 | POLB (0.47) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL15071561 | 0.86 | LGALS9 (0.40) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL16258710 | 0.86 | POLB (0.47) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL21007945 | 0.86 | POLB (0.47) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL15394247 | 0.86 | LGALS9 (0.40) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605018-B2 | Substituted nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2017-03-28 | — | — | US | disclosed |