SCHEMBL18671998

SCHEMBL18671998

CCCCCc1cccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6ccc7c(c6)c6cc(-n8c9ccccc9c9ccccc98)ccc6n7-c6cccc(CC(C)(C)C)c6)ccc54)ccc32)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.39
RORC P51449 1/20 0.39
RORB Q92753 1/20 0.39
DHFR P00374 2/20 0.35
TSPO P30536 3/20 0.34
LPL P06858 2/20 0.34
LIPG Q9Y5X9 2/20 0.34
CNR2 P34972 3/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ICMT O60725 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8739908 0.89 RORA (0.46) RORARORCRORBDHFRLPL
SCHEMBL26048120 0.88 KDM4E (0.43) RORARORCRORBTSPOCNR2
SCHEMBL16151832 0.86 TSPO (0.42) RORARORCRORBTSPOCNR2
SCHEMBL8739909 0.86 KDM4E (0.43) PPARGKDM4EATML3MBTL1
SCHEMBL14849242 0.84 KDM4E (0.33) TSPOKDM4EATML3MBTL1
SCHEMBL23072562 0.84 RORA (0.34) RORARORCRORBDHFRCNR2
SCHEMBL24914710 0.84 TSPO (0.43) RORARORCRORBTSPOCNR2
SCHEMBL29328807 0.82 HSD11B1 (0.45) RORARORCRORBTSPOICMT
SCHEMBL10108429 0.82 TSPO (0.39) RORARORCRORBTSPOKDM4E
SCHEMBL8739896 0.81 KDM4E (0.41) RORARORCRORBTSPOCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171293-B2 Organic electroluminescent element, material for organic electroluminescent element, light emitting device, display device and lighting device each using said element, and compound used for said element UDC IRELAND LIMITED (IE) 2021-11-09 US disclosed
US-10297760-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2019-05-21 US disclosed
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LTD (IE) 2018-04-12 US disclosed
US-9812650-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element UDC IRELAND LIMITED (IE) 2017-11-07 US disclosed
US-9608207-B2 Organic electroluminescence element UDC IRELAND LIMITED (IE) 2017-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10297760-B2 Organic electroluminescent element, compound and material for organic electroluminescent element, used in the same, and light emitting device, display device and illumination device, using the element RPS10, RPS20, RPS19 RORA 219/4885RORC 488/4885RORB 275/4885
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT RPS10, RPS20, RPS19 RORA 219/4885RORC 488/4885RORB 275/4885
US-11171293-B2 Organic electroluminescent element, material for organic electroluminescent element, light emitting device, display device and lighting device each using said element, and compound used for said element L1CAM, OR10J3, INTS9 RORA 187/4885RORC 584/4885RORB 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.