Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855190 | 0.86 | GBA1 (0.42) | GBA1 | |
| SCHEMBL18672449 | 0.85 | AOC3 (0.30) | — | |
| SCHEMBL179535 | 0.82 | GBA1 (0.44) | GBA1 | |
| SCHEMBL19727230 | 0.81 | GBA1 (0.39) | GBA1 | |
| SCHEMBL19420653 | 0.76 | GBA1 (0.31) | GBA1 | |
| SCHEMBL19440426 | 0.75 | GBA1 (0.50) | GBA1 | |
| SCHEMBL18672477 | 0.75 | CYP11B1 (0.35) | GBA1 | |
| SCHEMBL21509903 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL14376626 | 0.74 | NOS3 (0.33) | — | |
| SCHEMBL18879242 | 0.73 | GPR84 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655892-B2 | Certain chemical entities, compositions and methods | INTELLIKINE LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9605003-B2 | Heterocyclic compounds and uses thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2017-03-28 | — | — | US | disclosed |