Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186186 | 0.92 | CNR2 (0.35) | CNR2OPRL1MAPK3MAPK1P2RX7 | |
| SCHEMBL186318 | 0.88 | CNR2 (0.37) | CNR2P2RX7 | |
| SCHEMBL185877 | 0.87 | P2RX7 (0.36) | CNR2P2RX7 | |
| SCHEMBL2808145 | 0.86 | CNR2 (0.36) | CNR2ALOX15OPRL1BACE1GCGR | |
| SCHEMBL185111 | 0.86 | CNR2 (0.36) | CNR2OPRL1MAPK3MAPK1P2RX7 | |
| SCHEMBL14857224 | 0.85 | CNR2 (0.33) | CNR2ALOX15OPRL1MAPK3MAPK1 | |
| SCHEMBL185024 | 0.84 | OPRL1 (0.36) | CNR2OPRL1 | |
| Hydrochloric Acid SCHEMBL2808081 | 0.81 | AKT2 (0.39) | CNR2ALOX15BACE1GCGRP2RX7 | |
| SCHEMBL13128961 | 0.79 | CNR2 (0.40) | CNR2P2RX7 | |
| SCHEMBL2808620 | 0.79 | OPRL1 (0.37) | CNR2ALOX15OPRL1BACE1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |