Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 17/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16532681 | 0.88 | ELANE (0.56) | ELANEF2PLAUALDH1A1 | |
| SCHEMBL18673502 | 0.88 | ELANE (0.65) | ELANEF2PLAUALDH1A1 | |
| SCHEMBL12069238 | 0.81 | SCN9A (0.70) | ELANEF2PLAUALDH1A1 | |
| SCHEMBL13885817 | 0.80 | ALDH1A1 (0.62) | ELANEF2PLAUALDH1A1NPC1 | |
| SCHEMBL3346981 | 0.79 | ELANE (0.62) | ELANEF2PLAU | |
| SCHEMBL6705737 | 0.76 | ELANE (0.70) | ELANEF2PLAU | |
| SCHEMBL18673618 | 0.76 | ELANE (0.46) | ELANEALDH1A1NPC1POLBSMN1; SMN2 | |
| SCHEMBL17782595 | 0.76 | ELANE (0.59) | ELANEF2PLAUPOLB | |
| SCHEMBL12069050 | 0.75 | ELANE (0.66) | ELANEF2PLAUALDH1A1 | |
| SCHEMBL14659429 | 0.75 | ADORA1 (0.84) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145034-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-9605005-B2 | Alkynyl alcohols and methods of use | GENENTECH, INC. (US) | 2017-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145034-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | NFKB2, NFKB1, RELA | ELANE 1188/4885F2 1432/4885PLAU 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.