SCHEMBL1867441

SCHEMBL1867441

C=CCC1C(O)[C@H](CO)O[C@@H]1n1ccc(=S)[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.54
SLC28A2 O43868 1/20 0.54
SLC29A1 Q99808 1/20 0.54
SLC28A3 Q9HAS3 1/20 0.54
P2RY14 Q15391 1/20 0.49
P2RY2 P41231 5/20 0.48
P2RY6 Q15077 4/20 0.48
P2RY4 P51582 3/20 0.48
PYGM P11217 3/20 0.41
TK2 O00142 2/20 0.40
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
MTOR P42345 1/20 0.39
MDM2 Q00987 1/20 0.39
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4474459 0.89 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4474462 0.89 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL21418839 0.83 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL34578 0.83 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL329270 0.83 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL9057418 0.83 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL6672543 0.83 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL21418661 0.83 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL34577 0.83 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL14544181 0.83 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841428-B2 Polynucleotide nanomechanical device that acts as an artificial ribosome and translates DNA signals into polymer assembly instructions NEW YORK UNIVERSITY (US) 2014-09-23 US disclosed
US-7943751-B2 Ladder copolymers NEW YORK UNIVERSITY (US) 2011-05-17 US disclosed
US-20090137738-A1 LADDER COPOLYMERS NEW YORK UNIVERSITY (US) 2009-05-28 US disclosed
US-7479548-B1 Nucleic acid based ladder copolymers NEW YORK UNIVERSITY (US) 2009-01-20 US disclosed
US-20090005329-A1 NUCLEIC ACID BASED LADDER COPOLYMERS NEW YORK UNIVERSITY (US) 2009-01-01 US disclosed
WO-2008127453-A2 NUCLEIC ACID-BASED TRANSLATION SYSTEM AND METHOD FOR DECODING NUCLEIC ACID ENCRYPTED MESSAGE GARIBOTTI ALEJANDRA V (US) 2008-10-23 WO disclosed
US-20080221315-A1 NUCLEIC ACID-BASED TRANSLATION SYSTEM AND METHOD FOR DECODING NUCLEIC ACID ENCRYPTED MESSAGE NEW YORK UNIVERSITY (US) 2008-09-11 US disclosed
WO-2006017432-A2 A POLYNUCLEOTIDE NANOMECHANICAL DEVICE THAT ACTS AS AN ARTIFICIAL RIBOSOME AND TRANSLATES DNA SIGNALS INTO POLYMER ASSEMBLY INSTRUCTIONS NEW YORK UNIVERSITY (US) 2006-02-16 WO disclosed
US-20060035255-A1 Polynucleotide nanomechanical device that acts as an artificial ribosome and translates DNA signals into polymer assembly instructions NEW YORK UNIVERSITY (US) 2006-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221315-A1 NUCLEIC ACID-BASED TRANSLATION SYSTEM AND METHOD FOR DECODING NUCLEIC ACID ENCRYPTED MESSAGE NSUN3, RNMT, RNGTT SLC28A1 929/4885SLC28A2 717/4885SLC29A1 672/4885
US-20090005329-A1 NUCLEIC ACID BASED LADDER COPOLYMERS POLL, POLM, POLRMT SLC28A1 2924/4885SLC28A2 3100/4885SLC29A1 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.