SCHEMBL18674459

SCHEMBL18674459

C=Cc1ccc(C[SiH2][Si](C)(C)Cc2ccc(C=C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
HDAC8 Q9BY41 2/20 0.35
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
ESR1 P03372 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19625559 0.83 ALDH1A1 (0.37) ALDH1A1MEN1TP53MAPTKMT2A
SCHEMBL8760301 0.77 ESR1 (0.52) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL28846222 0.77 ALDH1A1 (0.50) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL619307 0.73 ALDH1A1 (0.46) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL15807759 0.73 ALDH1A1 (0.46) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL28846186 0.73 ALDH1A1 (0.46) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL9715846 0.73 ALDH1A1 (0.46) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL9509524 0.73 ALDH1A1 (0.46) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL10523793 0.73 ALDH1A1 (0.46) ALDH1A1HDAC8MEN1TP53MAPT
SCHEMBL10626255 0.73 ALDH1A1 (0.46) ALDH1A1HDAC8MEN1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170090248-A1 MANUFACTURING METHOD OF QUANTUM DOT-CONTAINING LAMINATED BODY, QUANTUM DOT-CONTAINING LAMINATED BODY, BACKLIGHT UNIT, LIQUID CRYSTAL DISPLAY DEVICE, AND QUANTUM DOT-CONTAINING COMPOSITION FUJIFILM CORPORATION (JP) 2017-03-30 US disclosed