Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320670 | 0.85 | HSD17B10 (0.46) | HSD17B10SSTR4MCL1CTSLCTSK | |
| SCHEMBL18675568 | 0.84 | HSD17B10 (0.45) | HSD17B10SSTR4MCL1DPP4CTSL | |
| SCHEMBL18681903 | 0.84 | HSD17B10 (0.48) | HSD17B10CTSLCTSKCTSBCTSS | |
| SCHEMBL17321816 | 0.79 | IDO1 (0.47) | HSD17B10CTSLCTSKCTSBCTSS | |
| SCHEMBL14263840 | 0.78 | SSTR4 (0.52) | SSTR4DPP4TACR3AKR1C1POLB | |
| SCHEMBL3560390 | 0.77 | SSTR4 (0.56) | HSD17B10SSTR4TACR3AKR1C1POLB | |
| SCHEMBL23343877 | 0.76 | POLB (0.50) | SSTR4DPP4TACR3AKR1C1POLB | |
| SCHEMBL28606841 | 0.76 | SSTR4 (0.50) | SSTR4DPP4TACR3AKR1C1POLB | |
| SCHEMBL17320671 | 0.75 | HSD17B10 (0.38) | HSD17B10MCL1DPP4POLBALDH1A1 | |
| SCHEMBL17321362 | 0.75 | NPSR1 (0.47) | HSD17B10CTSLCTSBCTSSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088520-A1 | DEUBIQUITINASE INHIBITORS | PHARMAKEA, INC. | 2017-03-30 | — | — | US | disclosed |
| US-20170088520-A1 | DEUBIQUITINASE INHIBITORS | PHARMAKEA, INC. | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088520-A1 | DEUBIQUITINASE INHIBITORS | USP30, USP1, USP28 | HSD17B10 2097/4885SSTR4 4514/4885MCL1 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.