Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718131 | 0.87 | PKM (0.59) | MAPTPKMPTGS1PTGS2MET | |
| SCHEMBL30394931 | 0.83 | MAPT (0.58) | MAPTPKMPTGS1PTGS2MET | |
| SCHEMBL9688979 | 0.83 | MAPT (0.58) | MAPTPKMPTGS1PTGS2MET | |
| SCHEMBL5770279 | 0.83 | MAPT (0.58) | MAPTPKMPTGS1PTGS2MET | |
| SCHEMBL7813366 | 0.79 | GAA (0.75) | MAPTGAATDP1KDM4EALDH1A1 | |
| SCHEMBL7813363 | 0.79 | GAA (0.75) | MAPTGAATDP1KDM4EALDH1A1 | |
| SCHEMBL9121535 | 0.79 | PKM (0.50) | MAPTPKMPTGS1PTGS2GAA | |
| SCHEMBL9121538 | 0.79 | PKM (0.50) | MAPTPKMPTGS1PTGS2GAA | |
| SCHEMBL28630446 | 0.77 | PKM (0.59) | MAPTPKMPTGS1PTGS2MET | |
| SCHEMBL9125332 | 0.77 | MEN1 (0.53) | MAPTPKMPTGS1PTGS2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110104739-A1 | BIOMARKERS FOR AMYOTROPHIC LATERAL SCLEROSIS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2011-05-05 | — | — | US | disclosed |