SCHEMBL718131

SCHEMBL718131

COc1cc(C=C(C(=O)O)C(=O)O)cc(OC)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.59
PTGS2 P35354 2/20 0.59
PTGS1 P23219 1/20 0.59
CYP3A4 P08684 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2B6 P20813 2/20 0.56
CYP2D6 P10635 1/20 0.56
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA3 P07451 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
MAPT P10636 5/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5770279 0.91 MAPT (0.58) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL9688979 0.91 MAPT (0.58) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL30394931 0.91 MAPT (0.58) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL1867644 0.87 SNCA (0.56) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL9121535 0.87 PKM (0.50) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL9121538 0.87 PKM (0.50) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL2897838 0.86 PKM (0.45) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL8630136 0.85 HTR1A (0.59) MAPTKMT2AGAATDP1KDM4E
SCHEMBL28630446 0.85 PKM (0.59) PKMPTGS2PTGS1CYP3A4CYP1A2
SCHEMBL9125332 0.85 MEN1 (0.53) PKMPTGS2PTGS1CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847784-B1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORP (US) 2017-07-05 EP claimed
EP-1871735-B1 ANTIOXIDANTS MERCK PATENT GMBH (DE) 2015-12-23 EP claimed
EP-1747773-B1 Photostable organic sunscreen compositions with antioxidant properties MERCK PATENT GMBH (DE) 2010-08-04 EP claimed
EP-1848507-B1 PREPARATION CONTAINING NANOPARTICULATE UV PROTECTION AGENTS MERCK PATENT GMBH (DE) 2009-08-05 EP claimed
CN-1826389-A Nanoparticulate UV protectant with silica coating MERCK PATENT GMBH (DE) 2006-08-30 CN claimed
CN-1798538-A Photostable organic sunscreen composition MERCK PATENT GMBH (DE) 2006-07-05 CN claimed
US-20260096977-A1 Compositions Containing a UV-Absorbing System Including Physical UV-Attenuating Material and Flavone L'OREAL (FR) 2026-04-09 US disclosed
US-20260096956-A1 NON-WHITENING MINERAL SUNSCREEN L'OREAL (FR) 2026-04-09 US disclosed
US-12589059-B2 Mineral sunscreen compositions with high SPF and shelf stability L'OREAL (FR) 2026-03-31 US disclosed
US-20260049218-A1 INTERFERENCE PIGMENTS MERCK PATENT GMBH (DE) 2026-02-19 US disclosed
EP-3592329-B1 USE OF COMPATIBLE SOLUTES SUSONITY Commercial GmbH (DE) 2026-02-18 EP disclosed
US-20260034037-A1 STABILIZED AVOBENZONE IN COSMETIC SUNSCREEN COMPOSITIONS BEIERSDORF AG (DE) 2026-02-05 US disclosed
US-20260034048-A1 STABILIZATION OF AVOBENZONE IN COSMETIC SUNSCREENS BEIERSDORF AG (DE) 2026-02-05 US disclosed
EP-2004136-A1 USE OF FLAVONOIDS Merck Patent GmbH (DE) 2008-12-24 EP disclosed
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives MERCK PATENT GMBH (DE) 2008-07-17 US disclosed
US-20080152603-A1 Antioxidants SUSONITY Commercial GmbH (DE) 2008-06-26 US disclosed
WO-2008025368-A1 USE OF CHROMEN-4-ONE DERIVATIVES MERCK PATENT GMBH (DE) 2008-03-06 WO disclosed
WO-2007118565-A1 USE OF FLAVONOIDS MERCK PATENT GMBH (DE) 2007-10-25 WO disclosed
CN-1826389-A Nanoparticulate UV protectant with silica coating MERCK PATENT GMBH (DE) 2006-08-30 CN disclosed
CN-1798538-A Photostable organic sunscreen composition MERCK PATENT GMBH (DE) 2006-07-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049218-A1 INTERFERENCE PIGMENTS SFN, VCL, FECH PKM 1631/4885PTGS2 653/4885PTGS1 2331/4885
US-20080152603-A1 Antioxidants GPX4, GPX1, CAT PKM 1176/4885PTGS2 320/4885PTGS1 262/4885
US-20260096956-A1 NON-WHITENING MINERAL SUNSCREEN SFN, CUTA, BRCA1 PKM 3333/4885PTGS2 2470/4885PTGS1 2391/4885
US-20260096977-A1 Compositions Containing a UV-Absorbing System Including Physical UV-Attenuating Material and Flavone SOD1, TFEB, KLF5 PKM 3126/4885PTGS2 3503/4885PTGS1 2661/4885
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives HPD, HAAO, UGT1A6 PKM 1127/4885PTGS2 1873/4885PTGS1 1937/4885
US-20260034037-A1 STABILIZED AVOBENZONE IN COSMETIC SUNSCREEN COMPOSITIONS TYR, RAD23B, CYP8B1 PKM 711/4885PTGS2 4257/4885PTGS1 4538/4885
US-20260034048-A1 STABILIZATION OF AVOBENZONE IN COSMETIC SUNSCREENS RUVBL1, CUTA, TTI1 PKM 1605/4885PTGS2 2741/4885PTGS1 2936/4885
US-12589059-B2 Mineral sunscreen compositions with high SPF and shelf stability CUTA, SLC39A3, SLC30A7 PKM 2595/4885PTGS2 885/4885PTGS1 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.