Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20026441 | 0.85 | MEN1 (0.40) | MEN1KMT2ANPC1HTTHPGD | |
| SCHEMBL28411171 | 0.84 | HTT (0.43) | MEN1KMT2ANPC1HTTHPGD | |
| SCHEMBL15020503 | 0.84 | MEN1 (0.45) | MEN1KMT2ANPC1HTTHPGD | |
| SCHEMBL7548107 | 0.84 | MEN1 (0.45) | MEN1KMT2ANPC1HTTHPGD | |
| SCHEMBL15486359 | 0.84 | MEN1 (0.45) | MEN1KMT2ANPC1HTTHPGD | |
| SCHEMBL28954561 | 0.83 | SMN1; SMN2 (0.42) | MEN1KMT2ANPC1HTTHPGD | |
| SCHEMBL28411267 | 0.83 | LMNA (0.46) | MEN1KMT2ANPC1HTTHPGD | |
| Hydrochloric Acid SCHEMBL6990702 | 0.83 | MEN1 (0.44) | MEN1KMT2ANPC1HTTHPGD | |
| SCHEMBL28413423 | 0.83 | L3MBTL1 (0.49) | MEN1KMT2AHTTHPGDSMN1; SMN2 | |
| SCHEMBL6998737 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2ANPC1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637705-B1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING S COLLEGE LONDON (GB) | 2017-03-29 | — | — | EP | disclosed |