Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 7/20 | 0.38 |
| ▸ | MAOB | P27338 | 7/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437792 | 0.82 | GSTP1 (0.59) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL16153115 | 0.74 | GSTP1 (0.55) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL14086107 | 0.71 | GSTP1 (0.42) | RAB9ANPC1SMN1; SMN2MAPTCRBN | |
| SCHEMBL31343967 | 0.71 | GSTP1 (0.58) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL13435046 | 0.69 | KMT2A (0.53) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL13461375 | 0.64 | KMT2A (0.39) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL18950712 | 0.63 | KCNH2 (0.34) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL17970190 | 0.62 | KMT2A (0.66) | RAB9ANPC1SMN1; SMN2MAPTGSTP1 | |
| SCHEMBL22434379 | 0.62 | MEN1 (0.62) | RAB9ANPC1SMN1; SMN2MAPTGSTP1 | |
| SCHEMBL1263370 | 0.61 | CA12 (0.54) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395358-B1 | Covalent tethering of functional groups to proteins | PROMEGA CORP (US) | 2017-03-29 | — | — | EP | disclosed |