Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14330482 | 0.87 | HDAC3 (0.33) | KMT2AHPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL16503905 | 0.82 | LMNA (0.33) | KMT2AHPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL13435046 | 0.81 | KMT2A (0.53) | KMT2AL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL31343967 | 0.80 | GSTP1 (0.58) | KMT2AL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL15976894 | 0.71 | HDAC3 (0.33) | KMT2AL3MBTL1HPGDSMN1; SMN2MAPT | |
| SCHEMBL4437789 | 0.71 | HPGD (0.40) | KMT2AL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL12951612 | 0.71 | GSTP1 (0.42) | KMT2AHPGDGSTP1HTTLMNA | |
| SCHEMBL12018901 | 0.71 | HDAC6 (0.34) | KMT2AL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4437792 | 0.70 | GSTP1 (0.59) | KMT2ANPC1RAB9AGSTP1HTT | |
| SCHEMBL4403233 | 0.69 | GSTP1 (0.41) | KMT2AGSTP1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075394-A1 | Method of Crosslinking Two Objects of Interest | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075394-A1 | Method of Crosslinking Two Objects of Interest | CD2BP2, FYN, ILK | KMT2A 3466/4885L3MBTL1 2203/4885HPGD 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.