Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.34 |
| ▸ | PARP1 | P09874 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4B | O94953 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355917 | 0.83 | ALDH1A1 (0.40) | ALDH1A1PDPK1PARP1SMN1; SMN2CA12 | |
| SCHEMBL2790086 | 0.75 | TDP1 (0.31) | LMNA | |
| SCHEMBL3245216 | 0.65 | ALDH1A1 (0.39) | ALDH1A1PDPK1PARP1SMN1; SMN2CA12 | |
| SCHEMBL29561093 | 0.65 | ALDH1A1 (0.39) | ALDH1A1PDPK1PARP1SMN1; SMN2CA12 | |
| SCHEMBL1919722 | 0.64 | — | — | |
| SCHEMBL14793587 | 0.64 | ALDH1A1 (0.38) | ALDH1A1PDPK1PARP1SMN1; SMN2CA12 | |
| SCHEMBL535022 | 0.64 | QTRT1 (0.42) | ALDH1A1ALOX15LMNAXDHBLM | |
| SCHEMBL14793621 | 0.64 | HPGD (0.38) | ALDH1A1PDPK1PARP1SMN1; SMN2CA12 | |
| SCHEMBL4455591 | 0.64 | — | — | |
| SCHEMBL8468924 | 0.60 | ALDH1A1 (0.41) | ALDH1A1PDPK1PARP1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499142-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | Advinus Therapeutics Limited (IN) | 2012-09-19 | — | — | EP | claimed |
| WO-2011055391-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-05-12 | — | — | WO | claimed |
| US-6060463-A | Treatment of conditions of abnormally increased intraocular pressure by administration of phosphonylmethoxyalkyl nucleoside analogs and related nucleoside analogs | Freeman, William (US) | 2000-05-09 | — | — | US | claimed |
| US-5869468-A | Treatment of conditions of abnormally increased intraocular pressure by administration of phosphonylmethoxyalkyl nucleoside analogs and related nucleoside analogs | FREEMAN WILLIAM R (US) | 1999-02-09 | — | — | US | claimed |
| EP-0754046-A1 | USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE | FREEMAN, William R. (US) | 1997-01-22 | — | — | EP | claimed |
| WO-1995026734-A1 | USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE | FREEMAN WILLIAM R (US) | 1995-10-12 | — | — | WO | claimed |
| EP-4587028-A2 | COMPOUNDS AND METHODS FOR IMPROVING HEALTH | Acurx Pharmaceuticals, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024086579-A2 | COMPOUNDS AND METHODS FOR IMPROVING HEALTH | Acurx Pharmaceuticals, Inc. (US) | 2024-04-25 | — | — | WO | disclosed |
| EP-4340827-A2 | USE OF IBEZAPOLSTAT TO PROMOTE MICROBIOME HEALTH | Acurx Pharmaceuticals, Inc. (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022266318-A2 | USE OF IBEZAPOLSTAT TO PROMOTE MICROBIOME HEALTH | ACURX PHARMACEUTICALS LLC (US) | 2022-12-22 | — | — | WO | disclosed |
| EP-2499142-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | Advinus Therapeutics Limited (IN) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011055391-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |
| EP-2185926-A1 | METHOD FOR DIAGNOSING ACUTE CARDIAC ISCHEMIA | Virginia Commonwealth University (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-0777417-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5631259-A | PURINE BASE DERIVATIVES FOR NUCLEOSIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| EP-0754046-A1 | USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE | FREEMAN, William R. (US) | 1997-01-22 | — | — | EP | disclosed |
| WO-1996004791-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PEST INSECTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1996-02-22 | — | — | WO | disclosed |
| WO-1995026734-A1 | USE OF PHOSPHONYLMETHOXYALKYL NUCLEOSIDES FOR THE TREATMENT OF RAISED INTRAOCULAR PRESSURE | FREEMAN WILLIAM R (US) | 1995-10-12 | — | — | WO | disclosed |
| EP-0521463-A2 | Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-07 | — | — | EP | disclosed |
| US-4241168-A | TWO-EQUIVALENT MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-23 | — | — | US | disclosed |