SCHEMBL1868014

SCHEMBL1868014

FC(F)(F)CCc1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1868845 0.88 TLR8 (0.32)
SCHEMBL1868563 0.86 CYSLTR2 (0.33)
SCHEMBL1870722 0.85 CYSLTR2 (0.35)
SCHEMBL1866608 0.85 CYSLTR2 (0.35)
SCHEMBL1862649 0.85 CYSLTR2 (0.35)
SCHEMBL1864907 0.85 CYSLTR2 (0.35)
SCHEMBL1864023 0.85 CYSLTR2 (0.35)
SCHEMBL216358 0.79
SCHEMBL6893184 0.79 RIPK1 (0.34)
SCHEMBL263226 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11731954-B2 Histone demethylase inhibitors CELGENE QUANTICEL RES INC (US) 2023-08-22 US claimed
US-20210238161-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2021-08-05 US claimed
US-11001568-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2021-05-11 US claimed
US-20200157077-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2020-05-21 US claimed
EP-3397617-A1 HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2018-11-07 EP claimed
US-10059687-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2018-08-28 US claimed
WO-2017117154-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2017-07-06 WO claimed
US-20170183325-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2017-06-29 US claimed
US-6150301-A Chemical abscission of fruits at low application rates WILCOX MERRILL (US) 2000-11-21 US claimed
WO-1997040681-A1 CHEMICAL ABSCISSION OF FRUITS AT LOW APPLICATION RATES WILCOX MERRILL (US) 1997-11-06 WO claimed
WO-1996038444-A1 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE SYNTHELABO (FR) 1996-12-05 WO claimed
US-11731954-B2 Histone demethylase inhibitors CELGENE QUANTICEL RES INC (US) 2023-08-22 US disclosed
US-20210238161-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2021-08-05 US disclosed
US-11001568-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2021-05-11 US disclosed
US-20200157077-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2020-05-21 US disclosed
EP-0805804-A1 SULPHONYL AMINO(THIO)CARBONYL-1,2,4-TRIAZOLIN(THI)ONE DERIVATIVES, THE PRODUCTION THEREOF AND THE USE THEREOF AS HERBICIDES BAYER AG (DE) 1997-11-12 EP disclosed
WO-1997040681-A1 CHEMICAL ABSCISSION OF FRUITS AT LOW APPLICATION RATES WILCOX MERRILL (US) 1997-11-06 WO disclosed
WO-1996022982-A1 SULPHONYL AMINO(THIO)CARBONYL-1,2,4-TRIAZOLIN(THI)ONE DERIVATIVES, THE PRODUCTION THEREOF AND THE USE THEREOF AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-08-01 WO disclosed
CN-1122333-A Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 1996-05-15 CN disclosed
US-4946611-A LUBRICANT, COMPATIBLE WITH FLON REFRIGERANTS IDEMITSU KOSAN CO., LTD. (JP) 1990-08-07 US disclosed