SCHEMBL263226

SCHEMBL263226

FC(F)(F)Cc1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19025852 0.81
SCHEMBL9620893 0.79
SCHEMBL1868014 0.78
SCHEMBL394425 0.77 RIPK1 (0.33)
SCHEMBL9586177 0.77
SCHEMBL8356703 0.77
SCHEMBL1868845 0.75 TLR8 (0.32)
SCHEMBL29020377 0.74 SLC6A2 (0.30)
SCHEMBL2698490 0.74 SLC6A2 (0.30)
SCHEMBL27337058 0.74 SLC6A2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11731954-B2 Histone demethylase inhibitors CELGENE QUANTICEL RES INC (US) 2023-08-22 US claimed
US-20210238161-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2021-08-05 US claimed
US-11001568-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2021-05-11 US claimed
US-20200157077-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2020-05-21 US claimed
EP-3397617-A1 HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2018-11-07 EP claimed
US-10059687-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2018-08-28 US claimed
WO-2017117154-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2017-07-06 WO claimed
US-20170183325-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. 2017-06-29 US claimed
CN-104203936-B Metalloenzyme inhibitor compounds 威尔金制药有限公司 2017-04-19 CN claimed
EP-2190054-B1 NONAQUEOUS ELECTROLYTE SOLUTION FOR SECONDARY BATTERY AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEM CORP (JP) 2016-10-26 EP claimed
WO-2005005382-A2 COMPOUNDS, COMPOSITIONS AND METHODS CYTOKINETICS, INC. (US) 2005-01-20 WO claimed
EP-1343561-A1 SERINE PROTEASE INHIBITORS Tularik Limited (GB) 2003-09-17 EP claimed
WO-2002047762-A1 SERINE PROTEASE INHIBITORS TULARIK LIMITED (GB) 2002-06-20 WO claimed
US-4512989-A IMIDOESTERS OR IMIDOTHIOESTERS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1985-04-23 US claimed
CN-117925215-A Electrochromic composition and electrochromic device 泰盈光电股份有限公司 2024-04-26 CN disclosed
US-20240085753-A1 ELECTROCHROMIC COMPOSITION AND ELECTROCHROMIC DEVICE TAI YING OPTRONICS CO., LTD. (TW) 2024-03-14 US disclosed
EP-3595072-B1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTIC SOLUTIONS, NON-AQUEOUS ELECTROLYTIC SOLUTION, AND ELECTRICAL STORAGE DEVICE SUMITOMO SEIKA CHEMICALS (JP) 2023-10-04 EP disclosed
EP-0075737-A1 N-Chlorocarbonyl-amino-acid esters, process for their preparation and their use Degussa Aktiengesellschaft (DE) 1983-04-06 EP disclosed
EP-0067698-A2 Optically active 1-aromatic-group-substituted-1-alkanones and methods for their manufacture SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1982-12-22 EP disclosed
EP-0000220-A1 Dihydrouracils, process for their preparation and pharmaceuticals containing them HOECHST AKTIENGESELLSCHAFT (DE) 1979-01-10 EP disclosed