Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.70 |
| ▸ | PRKCA | P17252 | 4/20 | 0.69 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.69 |
| ▸ | PRKCG | P05129 | 3/20 | 0.69 |
| ▸ | PRKCB | P05771 | 3/20 | 0.69 |
| ▸ | PRKCH | P24723 | 3/20 | 0.69 |
| ▸ | PRKCI | P41743 | 3/20 | 0.69 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.69 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.69 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.69 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18628825 | 1.00 | PTGS2 (0.70) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL18399996 | 1.00 | PTGS2 (0.70) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL17367889 | 1.00 | PTGS2 (0.70) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL18687212 | 1.00 | PTGS2 (0.70) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL15423127 | 1.00 | PTGS2 (0.70) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL29762786 | 0.92 | PRKCA (0.79) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL19344745 | 0.92 | PRKCA (0.79) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL1537765 | 0.92 | PRKCA (0.79) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL18399927 | 0.90 | PTGS2 (0.64) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL15423106 | 0.90 | PTGS2 (0.64) | PTGS2PRKCAPRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096386-A1 | Compositions And Methods Of Use Of Phorbol Esters For Treatment of Stroke | CHANG RICHARD L (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170096386-A1 | Compositions And Methods Of Use Of Phorbol Esters For Treatment of Stroke | CHANG RICHARD L (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170087112-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | BIOSUCCESS BIOTECH CO. LTD. (US) | 2017-03-30 | — | — | US | disclosed |
| US-20170087112-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | BIOSUCCESS BIOTECH CO. LTD. (US) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087112-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | PMAIP1, EBP, PLAT | PTGS2 258/4885PRKCA 13/4885PRKD3 460/4885 |
| US-20170096386-A1 | Compositions And Methods Of Use Of Phorbol Esters For Treatment of Stroke | PMAIP1, PLAT, EBP | PTGS2 229/4885PRKCA 15/4885PRKD3 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.