Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | PRKCA | P17252 | 5/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.62 |
| ▸ | PRKCG | P05129 | 4/20 | 0.62 |
| ▸ | PRKCB | P05771 | 4/20 | 0.62 |
| ▸ | PRKCH | P24723 | 4/20 | 0.62 |
| ▸ | PRKCI | P41743 | 4/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399927 | 1.00 | PTGS2 (0.64) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL18628313 | 0.93 | PRKCA (0.71) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL30194475 | 0.93 | PRKCA (0.71) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL15423138 | 0.93 | PRKCA (0.71) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL16922842 | 0.93 | PRKCA (0.71) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL362736 | 0.93 | PRKCA (0.71) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL21981002 | 0.93 | PRKCA (0.71) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL18399929 | 0.93 | PRKCA (0.71) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL12925016 | 0.92 | PRKCA (0.65) | PTGS2PRKCAPRKD3PRKCGPRKCB | |
| Ammonia Solution, Strong SCHEMBL5508975 | 0.92 | PRKCA (0.70) | PTGS2PRKCAPRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192521-A1 | SYNTHESIS OF TIGILANOL TIGLATE AND ANALOGS THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-09-15 | — | — | WO | disclosed |
| US-20210000780-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | BIOSUCCESS BIOTECH CO. LTD. (US) | 2021-01-07 | — | — | US | disclosed |
| US-10882815-B2 | Compositions and methods of use of phorbol esters in the treatment of neoplasms | BIOSUCCESS BIOTECH CO., LTD. (US) | 2021-01-05 | — | — | US | disclosed |
| US-10806714-B2 | Compositions and methods of use of phorbol esters in the treatment of neoplasms | BIOSUCCESS BIOTECH CO., LTD. (US) | 2020-10-20 | — | — | US | disclosed |
| US-10722484-B2 | Methods of cancer treatment | K-GEN, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-20200138829-A1 | METHODS OF CANCER TREATMENT | Ferro Therapeutics, Inc. | 2020-05-07 | — | — | US | disclosed |
| US-20190298679-A1 | METHODS OF CANCER TREATMENT | K-GEN THERAPEUTICS, INC. | 2019-10-03 | — | — | US | disclosed |
| US-20190216763-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | BIOSUCCESS BIOTECH CO. LTD. (US) | 2019-07-18 | — | — | US | disclosed |
| US-10278934-B2 | Compositions and methods of use of phorbol esters in the treatment of neoplasms | BIOSUCCESS BIOTECH CO., LTD. (US) | 2019-05-07 | — | — | US | disclosed |
| US-20190002390-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | BIOSUCCESS BIOTECH CO. LTD. (US) | 2019-01-03 | — | — | US | disclosed |
| US-20150072960-A1 | Compositions And Methods Of Use Of Phorbol Esters In The Treatment Of Neoplasms | BIOSUCCESS BIOTECH CO. LTD. (US) | 2015-03-12 | — | — | US | disclosed |
| US-20150072960-A1 | Compositions And Methods Of Use Of Phorbol Esters In The Treatment Of Neoplasms | BIOSUCCESS BIOTECH CO. LTD. (US) | 2015-03-12 | — | — | US | disclosed |
| US-20150071908-A1 | Compositions And Methods Of Use Of Phorbol Esters For the Treatment Of Stroke | BIOSUCCESS BIOTECH CO. LTD. (US) | 2015-03-12 | — | — | US | disclosed |
| US-20150071908-A1 | Compositions And Methods Of Use Of Phorbol Esters For the Treatment Of Stroke | BIOSUCCESS BIOTECH CO. LTD. (US) | 2015-03-12 | — | — | US | disclosed |
| US-20140140979-A1 | Compositions And Methods Of Use of Phorbol Esters For Treatment of Stroke | BIOSUCCESS BIOTECH CO. LTD. (US) | 2014-05-22 | — | — | US | disclosed |
| US-20140140979-A1 | Compositions And Methods Of Use of Phorbol Esters For Treatment of Stroke | BIOSUCCESS BIOTECH CO. LTD. (US) | 2014-05-22 | — | — | US | disclosed |
| US-20140018329-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | BIOSUCCESS BIOTECH CO., LTD. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20140018329-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | BIOSUCCESS BIOTECH CO., LTD. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20140011873-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | BIOSUCCESS BIOTECH CO., LTD (US) | 2014-01-09 | — | — | US | disclosed |
| US-20140011873-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | BIOSUCCESS BIOTECH CO., LTD (US) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011873-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS FOR THE TREATMENT OF STROKE | PMAIP1, EBP, PLAT | PTGS2 258/4885PRKCA 13/4885PRKD3 460/4885 |
| US-10278934-B2 | Compositions and methods of use of phorbol esters in the treatment of neoplasms | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
| US-20200138829-A1 | METHODS OF CANCER TREATMENT | AIFM2, GPX4, DDIT3 | PTGS2 270/4885PRKCA 953/4885PRKD3 1478/4885 |
| US-20190298679-A1 | METHODS OF CANCER TREATMENT | PRKCI, PRKCH, PRKCZ | PTGS2 1982/4885PRKCA 4/4885PRKD3 43/4885 |
| US-20210000780-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
| US-10722484-B2 | Methods of cancer treatment | PRKCI, PRKCH, PRKCZ | PTGS2 1982/4885PRKCA 4/4885PRKD3 43/4885 |
| US-20140018329-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
| US-20140140979-A1 | Compositions And Methods Of Use of Phorbol Esters For Treatment of Stroke | PMAIP1, PLAT, EBP | PTGS2 229/4885PRKCA 15/4885PRKD3 443/4885 |
| US-10882815-B2 | Compositions and methods of use of phorbol esters in the treatment of neoplasms | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
| US-10806714-B2 | Compositions and methods of use of phorbol esters in the treatment of neoplasms | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
| US-20190216763-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
| US-20150071908-A1 | Compositions And Methods Of Use Of Phorbol Esters For the Treatment Of Stroke | PMAIP1, EBP, PLAT | PTGS2 258/4885PRKCA 13/4885PRKD3 460/4885 |
| US-20190002390-A1 | COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
| US-20150072960-A1 | Compositions And Methods Of Use Of Phorbol Esters In The Treatment Of Neoplasms | PMAIP1, MYD88, HRAS | PTGS2 569/4885PRKCA 15/4885PRKD3 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.