Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31500714 | 0.70 | HKDC1 (0.32) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL15365325 | 0.69 | CA1 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL18995311 | 0.67 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL15374082 | 0.67 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL30640460 | 0.66 | CTSB (0.42) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL3267567 | 0.66 | CTSB (0.42) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL19457535 | 0.66 | ALDH1A1 (0.33) | ALDH1A1KDM4ELMNAGAAHPGD | |
| Hydrochloric Acid SCHEMBL11797987 | 0.64 | CTSB (0.41) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL18683016 | 0.62 | CYP1A1 (0.33) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL28128739 | 0.62 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855456-B1 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2017-03-29 | — | — | EP | disclosed |