Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371125 | 0.83 | KDM4E (0.40) | RAD52MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL2668601 | 0.81 | ALDH1A1 (0.42) | MEN1ALDH1A1LMNAGAAALOX12 | |
| SCHEMBL7893718 | 0.80 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL18922344 | 0.76 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL1956284 | 0.75 | GNAI3 (0.52) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL18922338 | 0.74 | GNAI3 (0.56) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL26748291 | 0.73 | GNAI3 (0.59) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL3411146 | 0.72 | GNAI3 (0.48) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL20626535 | 0.72 | SOS1 (0.51) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL17102129 | 0.72 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SOS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147283-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | North China Pharmaceutical Company., Ltd. (CN) | 2017-03-29 | — | — | EP | disclosed |