Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 9/20 | 0.36 |
| ▸ | CDK2 | P24941 | 9/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18684025 | 0.90 | CCNA2 (0.38) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL18684006 | 0.88 | EGFR (0.33) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL18683881 | 0.87 | SORD (0.40) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL18684004 | 0.83 | SLC27A1 (0.34) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL18684003 | 0.83 | SLC27A1 (0.34) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL18684005 | 0.81 | PANK3 (0.39) | ALDH1A1MEN1KMT2ATRPV3LMNA | |
| SCHEMBL18683973 | 0.81 | CCNA2 (0.31) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL4071055 | 0.80 | CETP (0.36) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL7715595 | 0.79 | CCNA2 (0.33) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL194327 | 0.79 | CCNA2 (0.33) | CCNA2CDK2CCNA1CDK5DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205609-B1 | HETEROCYCLE SUBSTITUTED PIPERAZINO DIHYDROTHIENO PYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-03-29 | — | — | EP | disclosed |