SCHEMBL18685461

SCHEMBL18685461

CCC(C)(CC)C(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NR3C1 P04150 1/20 0.30
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18824136 0.89 ELANE (0.35) RIPK1
SCHEMBL24015360 0.84 ELANE (0.37) TSHRSMN1; SMN2
SCHEMBL106867 0.83 RIPK1 (0.37) TSHRSMN1; SMN2NR3C1RIPK1
SCHEMBL19105276 0.79 TSHR (0.35) TSHRSMN1; SMN2NR3C1
SCHEMBL12027013 0.78 ELANE (0.45) TSHRSMN1; SMN2NR3C1
SCHEMBL21389209 0.78 DGAT1 (0.34) TSHRSMN1; SMN2NR3C1
SCHEMBL7490527 0.76 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL14747379 0.76 RIPK1 (0.33) NR3C1RIPK1
SCHEMBL19105207 0.76 NR3C1 (0.35) TSHRSMN1; SMN2NR3C1
SCHEMBL13917867 0.76 NR3C1 (0.35) TSHRSMN1; SMN2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3147334-A1 SURFACE TREATMENT LIQUID TOKYO OHKA KOGYO CO., LTD. (JP) 2017-03-29 EP disclosed