Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17413137 | 0.73 | ADRA1A (0.36) | ADRA1DADRA1A | |
| SCHEMBL24936110 | 0.66 | — | — | |
| SCHEMBL15889956 | 0.65 | ADRA1A (0.33) | ADRA1DADRA1A | |
| SCHEMBL15889955 | 0.63 | ADRA1A (0.31) | ADRA1DADRA1A | |
| SCHEMBL15890083 | 0.63 | ADRA1A (0.31) | ADRA1DADRA1A | |
| SCHEMBL27039175 | 0.63 | ADRA1A (0.33) | ADRA1DADRA1A | |
| SCHEMBL15889974 | 0.63 | ADRA1A (0.31) | ADRA1DADRA1A | |
| SCHEMBL19937611 | 0.63 | ADRA1A (0.31) | ADRA1DADRA1A | |
| SCHEMBL15889962 | 0.63 | ADRA1A (0.31) | ADRA1DADRA1A | |
| SCHEMBL15890085 | 0.63 | ADRA1A (0.31) | ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10028942-B2 | 3-substituted pyrazoles and uses thereof | GENENTECH, INC. (US) | 2018-07-24 | — | — | US | disclosed |
| US-20170087137-A1 | 3-SUBSTITUTED PYRAZOLES AND USES THEREOF | GENENTECH, INC. (US) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087137-A1 | 3-SUBSTITUTED PYRAZOLES AND USES THEREOF | PDXK, NLK, PDK3 | ADRA1D 2380/4885ADRA1A 2877/4885 |
| US-10028942-B2 | 3-substituted pyrazoles and uses thereof | PDXK, NLK, PDK3 | ADRA1D 2380/4885ADRA1A 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.