Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.61 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.61 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 4/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832597 | 1.00 | ALDH1A1 (0.65) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL18686193 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL18686192 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL4256569 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL18144902 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL2976354 | 0.80 | AKR1B1 (0.76) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL1504213 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL379054 | 0.79 | ALDH1A1 (0.67) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL2769879 | 0.79 | ALDH1A1 (0.67) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL2318176 | 0.79 | ALDH1A1 (0.67) | ALDH1A1CSNK2A1CSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935252-B1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | UNIV GRONINGEN (NL) | 2017-04-05 | — | — | EP | claimed |