Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18686193 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL18686191 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL15832597 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL5319417 | 0.73 | KDM4E (0.78) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL5563599 | 0.70 | KDM4E (0.61) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL5564432 | 0.70 | PIM1 (0.68) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL11252347 | 0.70 | SIGMAR1 (0.59) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL15825468 | 0.68 | MAOB (0.70) | ALDH1A1AKR1B1THRBPOLBMAPT | |
| SCHEMBL15825467 | 0.68 | MAOB (0.70) | ALDH1A1AKR1B1THRBPOLBMAPT | |
| SCHEMBL5563750 | 0.68 | ALDH1A1 (0.55) | ALDH1A1KDM4ECSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935252-B1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | UNIV GRONINGEN (NL) | 2017-04-05 | — | — | EP | claimed |
| EP-2935252-B1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | UNIV GRONINGEN (NL) | 2017-04-05 | — | — | EP | disclosed |