Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435279 | 1.00 | FOLH1 (0.41) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL27250381 | 1.00 | FOLH1 (0.41) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL12392036 | 0.94 | FOLH1 (0.35) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL22536882 | 0.86 | GABRR1 (0.41) | — | |
| SCHEMBL12812737 | 0.84 | SIRT6 (0.39) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL13573523 | 0.83 | FOLH1 (0.40) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL27250343 | 0.83 | FOLH1 (0.40) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL7604714 | 0.83 | FOLH1 (0.40) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL22062262 | 0.82 | CA1 (0.44) | — | |
| SCHEMBL14961163 | 0.81 | SIRT6 (0.43) | FOLH1GSRSIRT6SIRT1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |
| WO-2017053619-A1 | GLYPICAN-3BINDING FIBRONECTIN BASED SCAFFLOLD MOLECULES | BRISTROL-MYERS SQUIBB COMPANY (US) | 2017-03-30 | — | — | WO | disclosed |